Last reviewed: 2026-09-03 • Editorial Standards

Fish Ranked by Purine Content

Evidence-based comparison — data from USDA+ODS-NIH PURINE DATABASE Release 2 (March 2025)

Lowest Purine Fish

#1cod, fresh97.9 mg
#2seabass, mixed species, raw107.3 mg
#3cod, atlantic, wild, raw110.3 mg
#4sardine, fermented (heshiko)116.3 mg
#5tuna, canned117.0 mg
#6Salmon119.3 mg
#7salmon, mixed species, raw119.4 mg
#8Japanese seabass119.5 mg
#9Chub mackerel122.1 mg
#10salmon, chum, raw124.7 mg

Highest Purine Fish

#36mackerel, canned246.0 mg
#35salmon, atlantic, farmed, raw249.9 mg
#34salmon, sockeye, wild, raw259.8 mg
#33anchovy, fresh303.9 mg
#32Sardine305.7 mg
#31anchovy, canned321.0 mg
#30herring, canned378.0 mg
#29sardine, canned399.0 mg
#28anchovy, raw411.0 mg
#27milt, cod559.9 mg

Category Average: 205.2 mg/100g

The average across 36 Fish foods with lab-measured data. Foods below this average are better-than-typical choices within this category.

How to Use This Ranking

The purine ranking is sorted from lowest to highest. Rank #1 is the lowest-purine food in the category. Foods in the top half (above median) should be consumed with more awareness of portion and frequency. The difference between adjacent ranks varies: in some categories, rank #5 and #10 might be only 10 mg apart; in others, the gap can be 100+ mg. Always check the actual milligram value, not just the position. Rankings do not account for fructose or alcohol — use individual food pages for a complete risk assessment.

ACR 2020 Guideline Context

The American College of Rheumatology recommends that gout patients focus on purine awareness rather than complete food group elimination. Within any category, there is a wide purine range. The goal is to shift toward lower-purine choices within categories you already eat, rather than eliminating entire food groups. This ranking helps you identify which specific items to prioritize and which to limit.

Japanese guidelines recommend under 400 mg of total dietary purines per day. Using this ranking, you can estimate how much of budget each food uses per typical serving.

How This Comparison Is Built

This comparison scores every food on three independent axes — purine content, fructose, and alcohol. Purine figures rely on the USDA+ODS-NIH PURINE DATABASE Release 2 (March 2025) and Kaneko et al. (Biol Pharm Bull 37(5):709-721, 2014, PMID: 24553148); fructose data comes from USDA SR28. Ratings follow ACR 2020: Safe when purine is under 50 mg and fructose under 2 g with no alcohol, Moderate between these, Avoid beyond, or whenever alcohol appears. Per-food data quality is flagged T1 (lab-measured), T2 (measured plus consensus), or T3 (category estimate).

This comparison is provided for informational purposes only and does not constitute medical advice. Individual tolerance to purines and fructose varies. Consult a healthcare professional for personalized dietary guidance. Last reviewed: 2026-09-03.

Frequently Asked Questions

Which fish is lowest in purines?
Among 36 fish with measured purine values, the lowest options include cod, fresh at 97.9 mg/100g and seabass, mixed species, raw at 107.3 mg/100g. White fish generally run lower than fatty fish and much lower than sardines and anchovies.
Is salmon bad for gout?
Salmon is a moderate-purine fish — typically 100-170 mg/100g depending on the entry, which is moderate rather than high. Most people with gout can eat salmon in normal portions a few times per week. It also provides omega-3s with anti-inflammatory properties, which some research suggests may be beneficial.
Which fish should I avoid with gout?
The highest-purine fish in our database include milt, cod at 559.9 mg/100g. Sardines, anchovies, herring, and mackerel are consistently at the top of the scale and are best avoided or strictly limited in gout care.