Last reviewed: 2026-09-03 • Editorial Standards
Evidence-based comparison — data from USDA+ODS-NIH PURINE DATABASE Release 2 (March 2025)
| Food | Fructose (g/100g) | Relative Risk |
|---|---|---|
| nectarines, fresh, region 1, n/a, yes - sugars, nf0008lt | 1.4 | Lower |
| grape juice, purple, from concentrate with added vitamin c, shelf stable | 7.3 | 5.2x higher |
Fructose raises uric acid independently of purines by accelerating purine degradation in the liver. The ACR 2020 guideline identifies high-fructose foods as independent gout risk factors. Choosing lower-fructose fruits helps manage uric acid without eliminating fruit from the diet.
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Each item here is scored by a three-factor risk engine covering purines, fructose, and alcohol. Purine values draw on the USDA+ODS-NIH PURINE DATABASE Release 2 (March 2025) and Kaneko et al. (Biol Pharm Bull 37(5):709-721, 2014, PMID: 24553148); fructose comes from USDA SR28 tables. Classification uses ACR 2020 thresholds — Safe under 50 mg purine and 2 g fructose with no alcohol, Moderate in between, Avoid above, or when alcohol is present. Each food page labels its data quality as T1 (lab-measured), T2 (measured plus consensus), or T3 (category estimate).
This comparison is provided for informational purposes only and does not constitute medical advice. Individual tolerance to purines and fructose varies. Consult a healthcare professional for personalized dietary guidance. Last reviewed: 2026-09-03.