Fructose Face-Off: peaches, raw, yes - sugar, nf00095d vs grapes, green, seedless, raw

Evidence-based comparison — data from USDA+ODS-NIH PURINE DATABASE Release 2 (March 2025)

Fructose Comparison

Food	Fructose (g/100g)	Relative Risk
peaches, raw, region 2, n/a, yes - sugar, nf00095d	1.2	Lower
grapes, green, seedless, raw	8.6	7.2x higher

Fructose raises uric acid independently of purines by accelerating purine degradation in the liver. The ACR 2020 guideline identifies high-fructose foods as independent gout risk factors. Choosing lower-fructose fruits helps manage uric acid without eliminating fruit from the diet.

Understanding Fructose and Uric Acid

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Why Fruit Selection Matters for Gout

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How This Comparison Is Built

Every food in this comparison has been evaluated using a three-factor risk engine that independently assesses purine content, fructose level, and alcohol presence. Purine values come from two primary references — the USDA+ODS-NIH PURINE DATABASE Release 2 (March 2025) and Kaneko et al. (Biol Pharm Bull 37(5):709-721, 2014, PMID: 24553148). Fructose data is sourced from USDA SR28 Food Composition Tables. The verdict system follows ACR 2020 guideline thresholds: Safe (purine <50 mg, fructose <2g, no alcohol), Moderate (purine 50-150 mg or fructose 2-5g), Avoid (purine >150 mg, fructose >5g, or alcohol present). Data quality is labeled T1 (lab-measured), T2 (measured + consensus), or T3 (category estimate) on each food's detail page.

This comparison is provided for informational purposes only and does not constitute medical advice. Individual tolerance to purines and fructose varies. Consult a healthcare professional for personalized dietary guidance. Last reviewed: 2026-09-03.

Frequently Asked Questions

Which has more fructose: peaches, raw, yes - sugar, nf00095d or grapes, green, seedless, raw?

grapes, green, seedless, raw contains 8.6g fructose per 100g — 7.2x more than peaches, raw, yes - sugar, nf00095d at 1.2g/100g. Fructose directly raises uric acid through hepatic ATP depletion, independent of purine content.

How does fruit fructose affect gout differently from purines?

Purines provide raw material for uric acid; fructose accelerates the body's own purine breakdown. A fruit can be low in purines but still raise gout risk through high fructose. The ACR 2020 guideline recognizes both as independent dietary triggers.