Last reviewed: 2026-09-03 • Editorial Standards
Evidence-based comparison — data from USDA+ODS-NIH PURINE DATABASE Release 2 (March 2025)
| Food | Fructose (g/100g) | Relative Risk |
|---|---|---|
| plantains, underripe, raw | 1.2 | Lower |
| apples, gala | 8.1 | 6.8x higher |
Fructose raises uric acid independently of purines by accelerating purine degradation in the liver. The ACR 2020 guideline identifies high-fructose foods as independent gout risk factors. Choosing lower-fructose fruits helps manage uric acid without eliminating fruit from the diet.
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Every food in this comparison has been evaluated using a three-factor risk engine that independently assesses purine content, fructose level, and alcohol presence. Purine values come from two primary references — the USDA+ODS-NIH PURINE DATABASE Release 2 (March 2025) and Kaneko et al. (Biol Pharm Bull 37(5):709-721, 2014, PMID: 24553148). Fructose data is sourced from USDA SR28 Food Composition Tables. The verdict system follows ACR 2020 guideline thresholds: Safe (purine <50 mg, fructose <2g, no alcohol), Moderate (purine 50-150 mg or fructose 2-5g), Avoid (purine >150 mg, fructose >5g, or alcohol present). Data quality is labeled T1 (lab-measured), T2 (measured + consensus), or T3 (category estimate) on each food's detail page.
This comparison is provided for informational purposes only and does not constitute medical advice. Individual tolerance to purines and fructose varies. Consult a healthcare professional for personalized dietary guidance. Last reviewed: 2026-09-03.