Last reviewed: 2026-09-03 • Editorial Standards

Shellfish Ranked by Purine Content

Evidence-based comparison — data from USDA+ODS-NIH PURINE DATABASE Release 2 (March 2025)

Lowest Purine Shellfish

#1Botan shrimp53.4 mg
#2squid organs, raw59.6 mg
#3Squid Organs59.6 mg
#4clams, canned62.0 mg
#5scallops, raw76.5 mg
#6Japanese scallop76.5 mg
#7Octopus Organs79.8 mg
#8octopus organs, raw79.9 mg
#9crab, red king, raw99.5 mg
#10Red king crab99.6 mg

Highest Purine Shellfish

#35crab ovary, raw152.4 mg
#34Spear squid160.5 mg
#33shrimp, raw (unspecified)166.5 mg
#32shrimp, raw (sand shrimp and pacific shrimp species)177.3 mg
#31shrimp, mixed species, farmed, raw182.4 mg
#30Oyster184.5 mg
#29Japanese flying squid186.8 mg
#28shrimp, deep-water221.6 mg
#27shrimp, raw, frozen (no further unspecified)234.0 mg
#26Oriental shrimp273.2 mg

Category Average: 131.6 mg/100g

The average across 35 Shellfish foods with lab-measured data. Foods below this average are better-than-typical choices within this category.

How to Use This Ranking

The purine ranking is sorted from lowest to highest. Rank #1 is the lowest-purine food in the category. Foods in the top half (above median) should be consumed with more awareness of portion and frequency. The difference between adjacent ranks varies: in some categories, rank #5 and #10 might be only 10 mg apart; in others, the gap can be 100+ mg. Always check the actual milligram value, not just the position. Rankings do not account for fructose or alcohol — use individual food pages for a complete risk assessment.

ACR 2020 Guideline Context

The American College of Rheumatology recommends that gout patients focus on purine awareness rather than complete food group elimination. Within any category, there is a wide purine range. The goal is to shift toward lower-purine choices within categories you already eat, rather than eliminating entire food groups. This ranking helps you identify which specific items to prioritize and which to limit.

Japanese guidelines recommend under 400 mg of total dietary purines per day. Using this ranking, you can estimate how much of budget each food uses per typical serving.

How This Comparison Is Built

Every food in this comparison passes through a three-factor risk model that looks at purines, fructose, and alcohol independently. Purine values are sourced from the USDA+ODS-NIH PURINE DATABASE Release 2 (March 2025) and Kaneko et al. (Biol Pharm Bull 37(5):709-721, 2014, PMID: 24553148), fructose from USDA SR28. Verdicts apply ACR 2020 limits — Safe means under 50 mg purine and 2 g fructose with no alcohol; Moderate falls between; Avoid exceeds these or contains alcohol. Data quality tiers (T1/T2/T3) are listed on each food's detail page.

This comparison is provided for informational purposes only and does not constitute medical advice. Individual tolerance to purines and fructose varies. Consult a healthcare professional for personalized dietary guidance. Last reviewed: 2026-09-03.

Frequently Asked Questions

Which shellfish is lowest in purines?
Among 35 shellfish with measured purine values, the lowest options include Botan shrimp at 53.4 mg/100g and squid organs, raw at 59.6 mg/100g. Shellfish vary widely — scallops and some clams run lower, while shrimp and crab run higher.
Is shrimp bad for gout?
Shrimp is one of the higher-purine shellfish — in the FoodCanEat database it ranges from roughly 180-230 mg per 100 g depending on the entry, well above the 50 mg low-risk threshold. That places it in the moderate-to-high risk category, best limited or eaten in small, occasional portions for people with gout.
Can I eat lobster and crab with gout?
Lobster is moderate (about 100-110 mg/100g) and workable occasionally; crab runs higher (roughly 150 mg/100g). Neither is in the highest-risk tier like sardines, but both should be limited, with portion size and frequency as the main levers.